Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25480265 | 0.91 | OPRM1 (0.36) | OPRM1OPRL1OPRK1HRH3EPHX2 | |
| SCHEMBL25881815 | 0.89 | OPRM1 (0.40) | OPRM1OPRL1OPRK1HRH3EPHX2 | |
| SCHEMBL27307184 | 0.88 | OPRM1 (0.38) | OPRM1OPRL1OPRK1HRH3EPHX2 | |
| SCHEMBL26506541 | 0.88 | OPRM1 (0.35) | OPRM1OPRL1OPRK1EPHX2 | |
| SCHEMBL24475299 | 0.86 | HRH3 (0.35) | OPRM1OPRL1HRH3 | |
| SCHEMBL27290168 | 0.85 | NCF1 (0.39) | OPRM1OPRL1OPRK1EPHX2 | |
| SCHEMBL22520631 | 0.84 | HRH3 (0.35) | OPRM1OPRL1OPRK1HRH3 | |
| SCHEMBL24233214 | 0.83 | HRH3 (0.35) | OPRM1OPRL1OPRK1HRH3EPHX2 | |
| SCHEMBL22520604 | 0.82 | HRH3 (0.36) | OPRM1OPRL1OPRK1HRH3 | |
| SCHEMBL24475333 | 0.82 | TSHR (0.36) | OPRM1OPRL1OPRK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235715-A1 | COMPOUNDS FOR INHIBITING OR DEGRADING ITK, COMPOSITIONS, COMPRISING THE SAME METHODS OF THEIR MAKING AND METHODS OF THEIR USE | NURIX THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |