Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 5/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | APOB | P04114 | 1/20 | 0.33 |
| ▸ | MTTP | P55157 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803513 | 1.00 | TRPV1 (0.39) | TRPV1NAMPTSOS1WDR5LIMK1 | |
| SCHEMBL29803297 | 0.93 | WDR5 (0.41) | TRPV1NAMPTSOS1WDR5 | |
| SCHEMBL24670307 | 0.93 | WDR5 (0.41) | TRPV1NAMPTSOS1WDR5 | |
| SCHEMBL24670309 | 0.93 | WDR5 (0.41) | TRPV1NAMPTSOS1WDR5 | |
| SCHEMBL29803599 | 0.92 | NAMPT (0.41) | TRPV1NAMPTPRMT5WDR77 | |
| SCHEMBL24671289 | 0.87 | NAMPT (0.40) | TRPV1NAMPTSOS1WDR5PRMT5 | |
| SCHEMBL29803446 | 0.87 | NAMPT (0.40) | TRPV1NAMPTSOS1WDR5PRMT5 | |
| SCHEMBL24671356 | 0.87 | NAMPT (0.40) | TRPV1NAMPTSOS1WDR5PRMT5 | |
| SCHEMBL24670731 | 0.86 | NAMPT (0.50) | TRPV1NAMPTSOS1WDR5LIMK1 | |
| SCHEMBL29803437 | 0.86 | NAMPT (0.50) | TRPV1NAMPTSOS1WDR5LIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |