Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803577 | 1.00 | NAMPT (0.55) | NAMPTSCN9ATMPRSS2PDK4ESR2 | |
| SCHEMBL29803443 | 0.96 | NAMPT (0.54) | NAMPTSCN9ATMPRSS2PDK4ESR2 | |
| SCHEMBL29803462 | 0.96 | NAMPT (0.52) | NAMPTSCN9ATMPRSS2PDK4ESR2 | |
| SCHEMBL24670154 | 0.96 | NAMPT (0.52) | NAMPTSCN9ATMPRSS2PDK4ESR2 | |
| SCHEMBL29803764 | 0.93 | NAMPT (0.53) | NAMPTSCN9APDK4JAK1GRM5 | |
| SCHEMBL24670716 | 0.93 | NAMPT (0.53) | NAMPTSCN9APDK4JAK1GRM5 | |
| SCHEMBL24671531 | 0.89 | NAMPT (0.54) | NAMPTSCN9ATMPRSS2PDK4ESR2 | |
| SCHEMBL29803468 | 0.89 | NAMPT (0.54) | NAMPTSCN9ATMPRSS2PDK4ESR2 | |
| SCHEMBL24670838 | 0.88 | NAMPT (0.49) | NAMPTSCN9APDK4JAK1GRM5 | |
| SCHEMBL24670852 | 0.88 | NAMPT (0.49) | NAMPTSCN9APDK4JAK1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |