Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 12/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670975 | 1.00 | NAMPT (0.39) | NAMPTSOS1MAPTNPC1ALDH1A1 | |
| SCHEMBL29803446 | 0.91 | NAMPT (0.40) | NAMPTSOS1MAPTALDH1A1LMNA | |
| SCHEMBL24671356 | 0.91 | NAMPT (0.40) | NAMPTSOS1MAPTALDH1A1LMNA | |
| SCHEMBL24671289 | 0.91 | NAMPT (0.40) | NAMPTSOS1MAPTALDH1A1LMNA | |
| SCHEMBL29803338 | 0.89 | NAMPT (0.38) | NAMPTMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29803536 | 0.87 | NAMPT (0.40) | NAMPTSOS1MAPTWNT3ACDK7 | |
| SCHEMBL24891728 | 0.87 | NAMPT (0.46) | NAMPTMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL29803599 | 0.87 | NAMPT (0.41) | NAMPTMAPTALDH1A1WNT3A | |
| SCHEMBL24671562 | 0.86 | NAMPT (0.41) | NAMPTMAPTNPC1ALDH1A1HPGD | |
| SCHEMBL24670317 | 0.86 | NAMPT (0.41) | NAMPTMAPTNPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |