Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 9/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670317 | 1.00 | NAMPT (0.41) | NAMPTMAPTLMNAHTTNPSR1 | |
| SCHEMBL24670975 | 0.86 | NAMPT (0.39) | NAMPTMAPTLMNAHTTNPSR1 | |
| SCHEMBL24671366 | 0.86 | NAMPT (0.39) | NAMPTMAPTLMNAHTTNPSR1 | |
| SCHEMBL24670288 | 0.86 | NAMPT (0.37) | NAMPTMAPTCDK9TP53 | |
| SCHEMBL24670858 | 0.86 | NAMPT (0.37) | NAMPTMAPTCDK9TP53 | |
| SCHEMBL24671373 | 0.85 | NAMPT (0.53) | NAMPTMAPTLMNAHTTNPSR1 | |
| SCHEMBL24669446 | 0.84 | NAMPT (0.46) | NAMPTMAPTALDH1A1NPC1HPGD | |
| SCHEMBL24669451 | 0.84 | NAMPT (0.46) | NAMPTMAPTALDH1A1NPC1HPGD | |
| SCHEMBL29803672 | 0.84 | NAMPT (0.35) | NAMPTMAPTLMNAHTTALDH1A1 | |
| SCHEMBL24670644 | 0.83 | CHRM1 (0.38) | NAMPTMAPTLMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |