Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29803698 | 0.94 | MAPT (0.39) | MAPTRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL24670492 | 0.91 | ALDH1A1 (0.44) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| Trifluoroacetic Acid SCHEMBL29803611 | 0.85 | MAPT (0.42) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL24671380 | 0.84 | MAPT (0.53) | MAPTRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL24670497 | 0.82 | MAPT (0.40) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL29802954 | 0.82 | MAPT (0.40) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL24669214 | 0.82 | NAMPT (0.52) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL24669855 | 0.81 | MAPT (0.37) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL24670528 | 0.78 | NAMPT (0.46) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL29802928 | 0.78 | HDAC1 (0.40) | MAPTRAB9ANPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | claimed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |