Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | QDPR | P09417 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803020 | 1.00 | TMPRSS2 (0.46) | TMPRSS2MAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL24671353 | 0.92 | TMPRSS2 (0.43) | TMPRSS2MAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL24670801 | 0.90 | TMPRSS2 (0.45) | TMPRSS2MAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL29803034 | 0.89 | TRPV1 (0.47) | TMPRSS2MAPTNAMPTMMP2MMP3 | |
| SCHEMBL29803743 | 0.89 | ALDH1A1 (0.46) | TMPRSS2MAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL29802922 | 0.87 | TMPRSS2 (0.53) | TMPRSS2MAPTNAMPTHTR1DSLC6A4 | |
| SCHEMBL24670713 | 0.87 | TMPRSS2 (0.57) | TMPRSS2MAPTKMT2ANAMPTPOLB | |
| SCHEMBL29803740 | 0.87 | TMPRSS2 (0.57) | TMPRSS2MAPTKMT2ANAMPTPOLB | |
| SCHEMBL24670219 | 0.87 | TMPRSS2 (0.58) | TMPRSS2NAMPT | |
| SCHEMBL29803093 | 0.87 | TMPRSS2 (0.58) | TMPRSS2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |