Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 5/20 | 0.45 |
| ▸ | HTR1D | P28221 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | QDPR | P09417 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669441 | 0.91 | TMPRSS2 (0.53) | TMPRSS2HTR1DSLC6A4QDPRNAMPT | |
| SCHEMBL24671261 | 0.90 | QDPR (0.43) | TMPRSS2HTR1DSLC6A4QDPRNAMPT | |
| SCHEMBL24671448 | 0.90 | TMPRSS2 (0.46) | TMPRSS2HTR1DSLC6A4QDPRNAMPT | |
| SCHEMBL29803020 | 0.90 | TMPRSS2 (0.46) | TMPRSS2HTR1DSLC6A4QDPRNAMPT | |
| SCHEMBL24671353 | 0.88 | TMPRSS2 (0.43) | TMPRSS2QDPRNAMPTKMT2APLAU | |
| SCHEMBL24670178 | 0.87 | TMPRSS2 (0.52) | TMPRSS2HTR1DSLC6A4NAMPTKMT2A | |
| SCHEMBL24670256 | 0.86 | NAMPT (0.51) | HTR1DQDPRNAMPTKMT2AMCHR1 | |
| SCHEMBL29802957 | 0.86 | TMPRSS2 (0.44) | TMPRSS2HTR1DSLC6A4NAMPTKMT2A | |
| SCHEMBL24670214 | 0.85 | TMPRSS2 (0.52) | TMPRSS2HTR1DSLC6A4KMT2AMAPT | |
| SCHEMBL29803378 | 0.85 | TMPRSS2 (0.52) | TMPRSS2HTR1DSLC6A4KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | claimed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |