Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345916 | 0.86 | DGAT1 (0.54) | NPC1RAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL24670311 | 0.83 | FLT1 (0.47) | NPC1RAB9AALDH1A1LMNAKMT2A | |
| SCHEMBL1951610 | 0.79 | DGAT1 (0.51) | NPC1RAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3341029 | 0.79 | SMN1; SMN2 (0.50) | NPC1RAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29278885 | 0.78 | NPC1 (0.50) | NPC1RAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29278887 | 0.78 | NPC1 (0.50) | NPC1RAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL403566 | 0.77 | KMT2A (0.46) | NPC1RAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1648482 | 0.77 | DGAT1 (0.59) | NPC1RAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13485811 | 0.77 | DGAT1 (0.63) | NPC1RAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27007857 | 0.77 | DGAT1 (0.63) | NPC1RAB9AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |