Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 14/20 | 0.38 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803265 | 1.00 | BTK (0.38) | BTKTMPRSS2WNT3ANAMPT | |
| SCHEMBL29802865 | 0.87 | TMPRSS2 (0.43) | BTKTMPRSS2 | |
| SCHEMBL29803345 | 0.87 | TMPRSS2 (0.43) | BTKTMPRSS2NAMPT | |
| SCHEMBL24671586 | 0.87 | TMPRSS2 (0.43) | BTKTMPRSS2NAMPT | |
| SCHEMBL29803478 | 0.86 | WNT3A (0.48) | WNT3A | |
| SCHEMBL24670980 | 0.86 | WNT3A (0.48) | WNT3A | |
| SCHEMBL24669391 | 0.84 | WDR5 (0.40) | BTKTMPRSS2 | |
| SCHEMBL29802872 | 0.84 | WDR5 (0.40) | BTKTMPRSS2 | |
| SCHEMBL24669604 | 0.83 | MAPT (0.38) | BTKNAMPT | |
| SCHEMBL29803228 | 0.83 | MAPT (0.38) | BTKNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |