SCHEMBL24671851

SCHEMBL24671851

c1ccc(-c2cccc(Nc3cccc(-c4ccccc4-c4ccccc4)c3)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.54
MAPT P10636 2/20 0.54
KMT2A Q03164 2/20 0.54
ALDH1A1 P00352 2/20 0.54
AR P10275 1/20 0.54
MGLL Q99685 1/20 0.50
SIRT2 Q8IXJ6 1/20 0.47
SIRT1 Q96EB6 1/20 0.47
EPHX2 P34913 1/20 0.46
TSHR P16473 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
CYP3A4 P08684 1/20 0.45
KDM4E B2RXH2 1/20 0.45
LMNA P02545 1/20 0.45
GAA P10253 1/20 0.45
GFER P55789 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
HSD17B10 Q99714 2/20 0.44
CA2 P00918 1/20 0.43
FDPS P14324 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24370053 0.96 ALDH1A1 (0.58) MEN1MAPTKMT2AALDH1A1AR
SCHEMBL16749674 0.94 MAPT (0.62) MEN1MAPTKMT2AALDH1A1AR
SCHEMBL12367625 0.92 ALDH1A1 (0.56) MEN1MAPTKMT2AALDH1A1AR
SCHEMBL24794266 0.92 ALDH1A1 (0.56) MEN1MAPTKMT2AALDH1A1AR
SCHEMBL23760544 0.91 MAPT (0.65) MEN1MAPTKMT2AALDH1A1AR
SCHEMBL24370394 0.90 ALDH1A1 (0.58) MEN1MAPTKMT2AALDH1A1AR
SCHEMBL3181560 0.89 ALDH1A1 (0.67) MEN1MAPTKMT2AALDH1A1AR
SCHEMBL29501296 0.89 ALDH1A1 (0.67) MEN1MAPTKMT2AALDH1A1AR
SCHEMBL18201524 0.88 ALDH1A1 (0.50) MEN1MAPTKMT2AALDH1A1AR
SCHEMBL26491158 0.88 EPHX2 (0.51) MEN1MAPTKMT2AALDH1A1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022250244-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2022-12-01 WO disclosed