SCHEMBL18201524

SCHEMBL18201524

c1ccc(-c2cccc(Nc3ccc(-c4ccccc4)c(-c4ccccc4)c3)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
MEN1 O00255 2/20 0.50
MAPT P10636 2/20 0.50
KMT2A Q03164 2/20 0.50
AR P10275 1/20 0.50
MGLL Q99685 1/20 0.47
SIRT2 Q8IXJ6 1/20 0.45
SIRT1 Q96EB6 1/20 0.45
APP P05067 1/20 0.45
TSHR P16473 2/20 0.44
HSD17B10 Q99714 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC6A2 P23975 1/20 0.44
MAPK1 P28482 1/20 0.44
PTGS2 P35354 1/20 0.44
HTR2B P41595 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23765071 0.93 ALDH1A1 (0.52) ALDH1A1MEN1MAPTKMT2AAR
SCHEMBL24911850 0.93 ALDH1A1 (0.52) ALDH1A1MEN1MAPTKMT2AAR
SCHEMBL23765055 0.90 ALDH1A1 (0.52) ALDH1A1MEN1MAPTKMT2AAR
SCHEMBL20531464 0.90 ALDH1A1 (0.52) ALDH1A1MEN1MAPTKMT2AAR
SCHEMBL16947038 0.90 ALDH1A1 (0.56) ALDH1A1MEN1MAPTKMT2AAR
SCHEMBL23822279 0.89 APP (0.41) ALDH1A1MEN1MAPTKMT2AAR
SCHEMBL24794266 0.89 ALDH1A1 (0.56) ALDH1A1MEN1MAPTKMT2AAR
SCHEMBL19511796 0.88 ALDH1A1 (0.48) ALDH1A1MEN1MAPTKMT2AAR
SCHEMBL20582564 0.88 ALDH1A1 (0.48) ALDH1A1MEN1MAPTKMT2AAR
SCHEMBL24671851 0.88 MEN1 (0.54) ALDH1A1MEN1MAPTKMT2AAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11332474-B2 Compound and organic light-emission device LG DISPLAY CO., LTD. (KR) 2022-05-17 US disclosed
US-20200048273-A1 COMPOUND AND ORGANIC LIGHT-EMISSION DEVICE LG DISPLAY CO., LTD. (KR) 2020-02-13 US disclosed
WO-2016175533-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2016-11-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200048273-A1 COMPOUND AND ORGANIC LIGHT-EMISSION DEVICE TRPC4, TRPA1, TRPC1 ALDH1A1 721/4885MEN1 2375/4885MAPT 293/4885
US-11332474-B2 Compound and organic light-emission device TRPC4, TRPA1, TRPC1 ALDH1A1 721/4885MEN1 2375/4885MAPT 293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.