Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16270678 | 1.00 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3KMT2AATM | |
| SCHEMBL270836 | 0.92 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3KMT2AATM | |
| SCHEMBL19633944 | 0.88 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3KMT2AATM | |
| SCHEMBL5865581 | 0.87 | KMT2A (0.47) | SLC6A2SLC6A4SLC6A3KMT2AATM | |
| SCHEMBL14322127 | 0.83 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3KMT2AATM | |
| SCHEMBL14282583 | 0.82 | MLKL (0.40) | KMT2ATSHR | |
| SCHEMBL17904266 | 0.80 | CHRNB2 (0.39) | SLC6A2SLC6A4SLC6A3KMT2AATM | |
| SCHEMBL10526789 | 0.78 | CHRNB2 (0.42) | SLC6A2SLC6A4SLC6A3KMT2AATM | |
| SCHEMBL1345605 | 0.75 | DAO (0.35) | HDAC8HDAC6 | |
| SCHEMBL8986300 | 0.75 | AKR1C3 (0.38) | KMT2AHDAC1HDAC8HDAC6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220267361-A1 | CORROLE-BASED FRAMEWORKS AND METHODS OF USE THEREOF | UNIVERSITY OF SOUTH FLORIDA | 2022-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267361-A1 | CORROLE-BASED FRAMEWORKS AND METHODS OF USE THEREOF | CA13, CA12, ERCC4 | SLC6A2 2305/4885SLC6A4 2140/4885SLC6A3 1915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.