SCHEMBL24672037

SCHEMBL24672037

Brc1ccc(C2=CCCC(c3ccccc3)=C2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
MAPK1 P28482 1/20 0.48
HTR2C P28335 3/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NR1H4 Q96RI1 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
DGAT1 O75907 1/20 0.33
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
MAPK13 O15264 1/20 0.33
GCGR P47871 1/20 0.33
MAPK12 P53778 1/20 0.33
MAPK11 Q15759 1/20 0.33
MAPK14 Q16539 1/20 0.33
AGTR1 P30556 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14339825 0.79 ALDH1A1 (0.39) ALDH1A1MAPK1HTR2CNPC1RAB9A
SCHEMBL18490803 0.77 ALDH1A1 (0.34) ALDH1A1MAPK1HTR2CSIGMAR1
SCHEMBL1042357 0.76 HTR2C (0.56) ALDH1A1MAPK1HTR2CSIGMAR1HPGD
SCHEMBL18562482 0.76 MAPT (0.56) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL24054446 0.76 ALDH1A1 (0.43) ALDH1A1MAPK1HTR2CNPC1RAB9A
SCHEMBL10830517 0.75 TSHR (0.39) ALDH1A1MAPK1NPC1RAB9ANFKB1
SCHEMBL15468624 0.73 MEN1 (0.37) ALDH1A1ADORA2AADORA1HPGD
SCHEMBL12993025 0.73 HSD17B10 (0.34) ALDH1A1HTR2CTDP1SIGMAR1ADORA2A
SCHEMBL25558991 0.71 MEN1 (0.36) ALDH1A1TDP1ADORA2AADORA1HPGD
SCHEMBL22186204 0.71 HTR7 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022250244-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2022-12-01 WO disclosed