SCHEMBL246726

SCHEMBL246726

C=CC(=O)OCCC[Si](O[SiH](C)C)(O[SiH](C)C)O[SiH](C)C

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.53
ALDH1A1 P00352 4/20 0.53
CYP3A4 P08684 2/20 0.53
HPGD P15428 1/20 0.53
TP53 P04637 3/20 0.44
HIF1A Q16665 3/20 0.44
HSD17B10 Q99714 1/20 0.44
THRB P10828 2/20 0.38
ATM Q13315 1/20 0.35
HCAR2 Q8TDS4 4/20 0.35
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21811062 0.98 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5701982 0.92 TSHR (0.49) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5701398 0.90 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5701447 0.87 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL3681347 0.85 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23645231 0.84 TSHR (0.54) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL247232 0.82 ATM (0.42) TSHRALDH1A1CYP3A4HPGDATM
SCHEMBL71730 0.81 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL441818 0.79 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
Ethylene SCHEMBL22126280 0.79 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078211-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESS THEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE DOW TORAY CO LTD (JP) 2026-03-19 US disclosed
US-20250381127-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER OREAL (FR) 2025-12-18 US disclosed
EP-4626941-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESSTHEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE Dow Toray Co., Ltd. (JP) 2025-10-08 EP disclosed
CN-120129707-A Solid particles of silicone-functional copolymer, method for producing same, and cosmetic containing same 陶氏东丽株式会社 2025-06-10 CN disclosed
WO-2025095111-A1 POLYMER, WATER REPELLENT AGENT, FIBER PRODUCT, AND METHOD FOR PRODUCING FIBER PRODUCT ダイキン工業株式会社 2025-05-08 WO disclosed
WO-2025061338-A1 SOLID COMPOSITION IN POWDER FORM COMPRISING A FILM-FORMING POLYMER IN THE SOLID STATE L'OREAL (FR) 2025-03-27 WO disclosed
WO-2025061352-A1 PROCESS FOR PREPARING A COSMETIC COMPOSITION COMPRISING A PULVERULENT PHASE AND A FILM-FORMING POLYMER SOLUBILIZED IN A VOLATILE SOLVENT; AND PIGMENT FORMULATION. L'OREAL (FR) 2025-03-27 WO disclosed
US-20250041171-A1 EMULSION COMPOSITIONS CONTAINING CARBOSILOXANE DENDRIMER COMPOUND AND AQUEOUS PHASE FILM FORMER L'OREAL (FR) 2025-02-06 US disclosed
EP-4452193-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER L'OREAL (FR) 2024-10-30 EP disclosed
CN-118382418-A Cosmetic composition comprising polyhydroxyalkanoate copolymer with (unsaturated) hydrocarbon-based chain and silicone polymer 欧莱雅 2024-07-23 CN disclosed
US-6291021-B1 MATERIAL COMPRISING PENDANT CARBOSILOXANE-DENDRIMER FUNCTIONAL VINYL-TYPE POLYMER COMPRISING CARBOSILOXANE DENDRIMER GROUP AND ACRYLIC RESIN WHICH DOES NOT CONTAIN PENDANT CARBOSILOXANE DENDRIMER STRUCTURE DOW CORNING TORAY SILICONE CO., LTD. (JP) 2001-09-18 US disclosed
US-6280748-B1 TREATING SKIN OR HAIR BY APPLYING TO SKIN OR HAIR COSMETIC PRODUCT COMPRISING SOLUTION OR DISPERSION OF POLYMER IN LIQUID SELECTED FROM SILICONE OILS, ORGANIC OILS, ALCOHOLS AND WATER, POLYMER HAVING CARBOSILOXANE DENDRIMER IN ITS SIDE CHAIN DOW CORNING TORAY SILICONE, LTD. (JP) 2001-08-28 US disclosed
US-6238745-B1 APPLYING CARBOSILOXANE POLYMER DOW CORNING TORAY SILICONE CO. LTD. (JP) 2001-05-29 US disclosed
EP-1095953-A2 Silicone-grafted vinyl copolymer emulsion composition Dow Corning Toray Silicone Company, Ltd. (JP) 2001-05-02 EP disclosed
EP-1055674-A1 BRANCHED SILOXANE/SILALKYLENE COPOLYMER, SILICONE-CONTAINING ORGANIC POLYMER, AND PROCESS FOR PRODUCING THE SAME Dow Corning Toray Silicone Company, Ltd. (JP) 2000-11-29 EP disclosed
EP-1013702-A2 Gas-permeable film Dow Corning Toray Silicone Company, Ltd. (JP) 2000-06-28 EP disclosed
EP-1013736-A2 Water repellent for treating solids Dow Corning Toray Silicone Company, Ltd. (JP) 2000-06-28 EP disclosed
EP-1011033-A2 Carrier, toner and electrophotographic photoreceptor comprising a carbosiloxane dendrimer-functional vinyl type polymer Dow Corning Toray Silicone Company, Ltd. (JP) 2000-06-21 EP disclosed
EP-1006165-A2 Coating material Dow Corning Toray Silicone Company, Ltd. (JP) 2000-06-07 EP disclosed
EP-0963751-A2 Cosmetic raw material, cosmetic product, and method for manufacturing cosmetic raw material Dow Corning Toray Silicone Company, Ltd. (JP) 1999-12-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078211-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESS THEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE FOXM1, FOXK1, TAF1L TSHR 2100/4885ALDH1A1 332/4885CYP3A4 2713/4885
US-20250381127-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER H1-0, PARN, FASN TSHR 1030/4885ALDH1A1 2361/4885CYP3A4 2587/4885
US-20250041171-A1 EMULSION COMPOSITIONS CONTAINING CARBOSILOXANE DENDRIMER COMPOUND AND AQUEOUS PHASE FILM FORMER CCNO, CUTA, SQLE TSHR 3701/4885ALDH1A1 1418/4885CYP3A4 3379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.