Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 18/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24672706 | 0.83 | NT5E (0.47) | NT5E | |
| SCHEMBL30008194 | 0.80 | NT5E (0.56) | NT5E | |
| SCHEMBL21348635 | 0.79 | NT5E (0.53) | NT5E | |
| SCHEMBL27414417 | 0.79 | NT5E (0.53) | NT5E | |
| SCHEMBL30008415 | 0.77 | NT5E (0.43) | NT5E | |
| SCHEMBL23337935 | 0.74 | NT5E (0.46) | NT5E | |
| SCHEMBL30008321 | 0.71 | NT5E (0.45) | NT5E | |
| SCHEMBL30008273 | 0.71 | LMNA (0.49) | NT5E | |
| SCHEMBL27414436 | 0.70 | NT5E (0.54) | NT5E | |
| SCHEMBL27414597 | 0.70 | NT5E (0.54) | NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237747-A1 | SMALL MOLECULAR CD73 ANTAGONIST AND USE THEREOF | 四川海思科制药有限公司 | 2022-11-17 | — | — | WO | disclosed |