Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27693802 | 0.85 | MAOA (0.51) | MAOAGAAMGAMSIMGAM2 | |
| SCHEMBL29254203 | 0.79 | MAOA (0.50) | MAOAGAAMGAMSIMGAM2 | |
| SCHEMBL2404775 | 0.78 | NPC1 (0.52) | MAOAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11344866 | 0.78 | MAOA (0.49) | MAOATOP2AKDM4EALDH1A1HPGD | |
| SCHEMBL8868142 | 0.77 | MAOA (0.46) | MAOAGAAMGAMSIMGAM2 | |
| SCHEMBL11408611 | 0.76 | EYA3 (0.44) | MAOAGAAKDM4EALDH1A1 | |
| SCHEMBL8867510 | 0.75 | MAOA (0.51) | MAOAGAAMGAMSIMGAM2 | |
| SCHEMBL18242393 | 0.75 | MAOA (0.45) | MAOAGAAMGAMSIMGAM2 | |
| SCHEMBL28284758 | 0.74 | MAOA (0.42) | MAOATOP2AKDM4EALDH1A1HPGD | |
| SCHEMBL2052391 | 0.74 | NQO1 (0.65) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011117690-A1 | HYDROXY-2,3-DIARYLXANTHONES AS THERAPEUTIC AGENTS OF PATHOLOGIES DUE TO REACTIVE OXYGEN SPECIES | UNIVERSIDADE DE AVEIRO (PT) | 2011-09-29 | — | — | WO | disclosed |