SCHEMBL24672946

SCHEMBL24672946

C[C@H](O)CN1CCN(C=O)CCN(C[C@H](C)O)CC1

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.63
PIK3CD O00329 1/20 0.38
DRD2 P14416 4/20 0.38
DRD3 P35462 4/20 0.38
DRD4 P21917 2/20 0.37
SLC6A3 Q01959 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
BRD4 O60885 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24672241 1.00 HSD17B10 (0.63) HSD17B10PIK3CDDRD2DRD3DRD4
SCHEMBL28902590 1.00 HSD17B10 (0.63) HSD17B10PIK3CDDRD2DRD3DRD4
SCHEMBL21814634 0.98 HSD17B10 (0.61) HSD17B10PIK3CDDRD2DRD3DRD4
SCHEMBL28368964 0.87 HSD17B10 (0.50) HSD17B10BRD4
SCHEMBL24672257 0.83 KDM4E (0.56) HSD17B10MEN1KMT2A
SCHEMBL4912947 0.83 HSD17B10 (0.57) HSD17B10PIK3CD
SCHEMBL13833151 0.82 DRD2 (0.47) PIK3CDDRD2DRD3DRD4SLC6A3
SCHEMBL17996818 0.82 DRD2 (0.47) PIK3CDDRD2DRD3DRD4SLC6A3
SCHEMBL5860445 0.82
SCHEMBL8860654 0.82 DRD2 (0.47) PIK3CDDRD2DRD3DRD4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204065-A1 IRON(III) MACROCYCLIC COMPLEXES WITH MIXED HYROXYL PENDANTS AS MRI CONTRAST AGENTS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-29 WO disclosed