⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26407897 | 0.77 | CA12 (0.46) | — | |
| SCHEMBL9915229 | 0.77 | — | — | |
| SCHEMBL20078681 | 0.75 | CA12 (0.36) | — | |
| SCHEMBL18699675 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL10822869 | 0.72 | — | — | |
| SCHEMBL3167379 | 0.72 | — | — | |
| SCHEMBL1286323 | 0.72 | — | — | |
| SCHEMBL14617690 | 0.72 | TAS2R38 (0.47) | — | |
| SCHEMBL99153 | 0.72 | — | — | |
| SCHEMBL16628521 | 0.70 | CA2 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230110180-A1 | CDK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-04-13 | — | — | US | disclosed |
| US-20220340570-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2022-10-27 | — | — | US | disclosed |