Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26406493 | 0.90 | KDM4E (0.36) | TP53SMN1; SMN2HTTSCN1ASCN2A | |
| SCHEMBL23559986 | 0.89 | HTT (0.34) | TP53SMN1; SMN2HTTSCN1ASCN2A | |
| SCHEMBL25477793 | 0.89 | ALDH1A1 (0.40) | TP53SMN1; SMN2SCN1ASCN2ASCN3A | |
| SCHEMBL25705791 | 0.88 | KDM4E (0.36) | SMN1; SMN2HTTKDM4EALDH1A1PRMT6 | |
| SCHEMBL23696532 | 0.87 | KDM4E (0.42) | TP53SMN1; SMN2HTTKDM4EALDH1A1 | |
| SCHEMBL24672987 | 0.87 | KDM4E (0.42) | TP53SMN1; SMN2HTTKDM4EALDH1A1 | |
| SCHEMBL24029376 | 0.87 | CARM1 (0.36) | TP53SMN1; SMN2SCN1ASCN2ASCN3A | |
| SCHEMBL25592552 | 0.86 | — | — | |
| SCHEMBL23696051 | 0.86 | SLC2A1 (0.35) | TP53SMN1; SMN2 | |
| SCHEMBL21106209 | 0.86 | TP53 (0.33) | TP53SMN1; SMN2HTTSCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303526-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-09-28 | — | — | US | disclosed |
| US-20230132715-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-05-04 | — | — | US | disclosed |
| US-20220340570-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2022-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230132715-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | TP53 1474/4885SMN1; SMN2 2647/4885HTT 2464/4885 |
| US-20220340570-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | TP53 1474/4885SMN1; SMN2 2647/4885HTT 2464/4885 |
| US-20230303526-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | TP53 1474/4885SMN1; SMN2 2647/4885HTT 2464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.