SCHEMBL24673970

SCHEMBL24673970

N#CN1CCC2(C[C@H](c3ccccc3)NC2=O)C1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
OTUD7B Q6GQQ9 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20721818 1.00 OTUD7B (0.65) OTUD7B
SCHEMBL20608099 0.79 OTUD7B (1.00) OTUD7B
SCHEMBL20607934 0.75 OTUD7B (0.56) OTUD7B
SCHEMBL13368587 0.74 LMNA (0.41) OTUD7B
SCHEMBL13342746 0.74 GRIN2D (0.44) OTUD7B
SCHEMBL20607923 0.72 OTUD7B (0.66) OTUD7B
SCHEMBL2604308 0.72 KDM1A (0.38)
SCHEMBL20607997 0.71 OTUD7B (1.00) OTUD7B
Hydrochloric Acid SCHEMBL3193010 0.71 KDM1A (0.38)
SCHEMBL20608017 0.70 OTUD7B (0.39) OTUD7B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4067355-A1 SPIRO-CONDENSED PYRROLIDINE DERIVATIVES AS DEUBIQUITYLATING ENZYME (DUB) INHIBITORS Mission Therapeutics Limited (GB) 2022-10-05 EP disclosed