SCHEMBL6556069

SCHEMBL6556069

O=C(Nc1ccccc1)c1ccc2cc(O)ccc2c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DEGS1 O15121 3/20 0.77
PLAU P00749 2/20 0.71
F2 P00734 1/20 0.68
PLG P00747 1/20 0.68
PLAT P00750 1/20 0.68
KLKB1 P03952 1/20 0.68
KLK1 P06870 1/20 0.68
PRSS1 P07477 1/20 0.68
NPC1 O15118 4/20 0.60
RAB9A P51151 4/20 0.60
KDM4E B2RXH2 2/20 0.60
MEN1 O00255 4/20 0.60
KMT2A Q03164 4/20 0.60
NR1H4 Q96RI1 1/20 0.58
GPR27 Q9NS67 1/20 0.58
CASP3 P42574 1/20 0.57
SENP7 Q9BQF6 1/20 0.57
PTPN1 P18031 1/20 0.56
HDAC2 Q92769 2/20 0.54
HDAC8 Q9BY41 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7064726 0.97 DEGS1 (0.77) DEGS1PLAUF2PLGPLAT
SCHEMBL29107200 0.91 DEGS1 (0.73) DEGS1PLAUF2PLGPLAT
SCHEMBL10191568 0.89 KMT2A (0.73) DEGS1PLAUF2PLGPLAT
SCHEMBL2467402 0.88 PLAU (0.78) DEGS1PLAUF2PLGPLAT
SCHEMBL29518660 0.87 DEGS1 (1.00) DEGS1PLAUF2PLGPLAT
SCHEMBL7890716 0.87 DEGS1 (1.00) DEGS1PLAUF2PLGPLAT
SCHEMBL14111908 0.86 PLAU (0.76) DEGS1PLAUF2PLGPLAT
SCHEMBL5433884 0.85 PLAU (0.58) DEGS1PLAUF2PLGPLAT
SCHEMBL29068810 0.84 DEGS1 (0.72) DEGS1PLAUNPC1RAB9AKDM4E
SCHEMBL12268571 0.82 DEGS1 (0.65) DEGS1PLAUPLGPLATNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115896222-A Enzymatic preparation method of cefalexin 河南康达制药有限公司 2023-04-04 CN claimed
CN-115896222-A Enzymatic preparation method of cefalexin 河南康达制药有限公司 2023-04-04 CN disclosed
EP-0872477-B1 NAPHTHOL DERIVATIVE AND PROCESS FOR PREPARING THE SAME UENO SEIYAKU OYO KENKYUJO KK (JP) 2004-12-22 EP disclosed
EP-1283205-B1 NAPHTHOL DERIVATIVES UENO SEIYAKU OYO KENKYUJO KK (JP) 2004-09-22 EP disclosed
EP-1283205-A1 NAPHTHOL DERIVATIVES KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2003-02-12 EP disclosed
US-6451988-B1 AN AZO COMPOUND AND A METAL COMPLEX WHICH ARE SYNTHESIZED WITH THE NAPHTHOL DERIVATIVE KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2002-09-17 US disclosed
US-6252104-B1 3,6-DISUBSTITUTED-2-OXYNAPHTHALENE DERIVATIVES; RAW MATERIALS FOR SYNTHESIS OF SUCH MATERIALS AS DYES, PIGMENTS, PHOTOSENSITIVE MATERIALS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2001-06-26 US disclosed
US-6084101-A Naphtol derivative and process for producing the same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2000-07-04 US disclosed
EP-0765858-B1 NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME UENO SEIYAKU OYO KENKYUJO KK (JP) 1999-12-22 EP disclosed
US-5847233-A Naphthol derivatives and process for producing the same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1998-12-08 US disclosed
EP-0872477-A1 NAPHTHOL DERIVATIVE AND PROCESS FOR PREPARING THE SAME KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1998-10-21 EP disclosed
US-5786523-A Naphthol derivatives and process for producing the same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1998-07-28 US disclosed
EP-0765858-A1 NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1997-04-02 EP disclosed