SCHEMBL24674409

SCHEMBL24674409

CC(C)c1nc2ccccc2n1-c1ccc(-c2c3ccccc3c(-c3ccc4ccccc4c3)c3cc(-c4ccccc4)ccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 3/20 0.44
CYP1A2 P05177 2/20 0.44
CRBN Q96SW2 1/20 0.42
MAPK10 P53779 1/20 0.38
ESR1 P03372 3/20 0.37
ESR2 Q92731 3/20 0.37
PIK3CD O00329 2/20 0.37
PIK3CA P42336 2/20 0.37
MTOR P42345 1/20 0.37
CNR2 P34972 1/20 0.36
PIK3CB P42338 1/20 0.36
PIK3CG P48736 1/20 0.36
KCNH2 Q12809 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
LMNA P02545 1/20 0.33
PDE7A Q13946 2/20 0.33
PDE7B Q9NP56 2/20 0.33
PTGER4 P35408 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24673723 0.95 CRBN (0.46) PDE10ACYP1A2CRBNESR1ESR2
SCHEMBL24674275 0.95 CRBN (0.46) PDE10ACYP1A2CRBNESR1ESR2
SCHEMBL24674134 0.95 CRBN (0.46) PDE10ACYP1A2CRBNESR1ESR2
SCHEMBL2604838 0.94 CRBN (0.47) PDE10ACYP1A2CRBNMAPK10ESR1
SCHEMBL2604825 0.92 CRBN (0.47) PDE10ACYP1A2CRBNMAPK10ESR1
SCHEMBL14499570 0.91 PDE10A (0.42) PDE10ACYP1A2CRBNMAPK10PIK3CD
SCHEMBL14499591 0.89 PDE10A (0.44) PDE10ACYP1A2CRBNMAPK10PIK3CD
SCHEMBL2604846 0.89 CRBN (0.47) PDE10ACYP1A2CRBNESR1ESR2
SCHEMBL2604828 0.89 CRBN (0.47) PDE10ACYP1A2CRBNESR1ESR2
SCHEMBL23022724 0.87 MAPK1 (0.51) PDE10ACYP1A2ESR1ESR2PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220384734-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220384734-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE MCOLN2, RER1, L1CAM PDE10A 4471/4885CYP1A2 2514/4885CRBN 818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.