Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28292686 | 0.83 | HTR2A (0.57) | ABL1GABRA1GABRB2HTR2AHTR2C | |
| SCHEMBL21037208 | 0.80 | ABL1 (0.39) | ABL1GABRA1GABRB2HTR2AHTR2C | |
| SCHEMBL18417279 | 0.79 | CYP19A1 (0.50) | ABL1GABRA1GABRB2HTR2AHTR2C | |
| SCHEMBL18417282 | 0.79 | CYP19A1 (0.50) | ABL1GABRA1GABRB2HTR2AHTR2C | |
| SCHEMBL30286452 | 0.79 | CYP19A1 (0.50) | ABL1GABRA1GABRB2HTR2AHTR2C | |
| SCHEMBL18899826 | 0.78 | ABL1 (0.56) | ABL1GABRA1GABRB2HTR2AHTR2C | |
| SCHEMBL17253659 | 0.78 | ABL1 (0.49) | ABL1GABRA1GABRB2HTR2AHTR2C | |
| SCHEMBL8240107 | 0.77 | CYP1A2 (0.56) | ALDH1A1LMNAAKR1C3 | |
| SCHEMBL17229344 | 0.77 | ABL1 (0.45) | ABL1GABRA1GABRB2HTR2AHTR2C | |
| SCHEMBL14511412 | 0.77 | PDPK1 (0.47) | ABL1GABRA1GABRB2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217990-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. | 2024-07-04 | — | — | US | disclosed |
| US-20220125786-A1 | SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | GLOBAL BLOOD THERAPEUTICS INC (US) | 2022-04-28 | — | — | US | disclosed |
| US-20210130473-A1 | TGFßR1 INHIBITOR-ASGR ANTIBODY CONJUGATES AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. | 2021-05-06 | — | — | US | disclosed |
| US-20210032229-A1 | PYRIDINE RING-SUBSTITUTED PYRIDAZINOL COMPOUNDS AND DERIVATIVES, PREPARATION METHODS, HERBICIDAL COMPOSITIONS AND APPLICATIONS THEREOF | QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) | 2021-02-04 | — | — | US | disclosed |
| US-10806733-B2 | Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2020-10-20 | — | — | US | disclosed |
| US-20200048288-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-02-13 | — | — | US | disclosed |
| US-20190160060-A1 | SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | GLOBAL BLOOD THERAPEUTICS, INC. | 2019-05-30 | — | — | US | disclosed |
| EP-3224252-B1 | SUBSTITUTED OXAZOLE- AND THIAZOLE-BASED CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS II | MEDIFRON DBT INC (KR) | 2019-01-09 | — | — | EP | disclosed |
| WO-2018115069-A1 | NITROGEN CONTAINING BICYCLIC DERIVATIVES FOR TREATING PAIN AND PAIN RELATED CONDITIONS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2018-06-28 | — | — | WO | disclosed |
| EP-3339307-A1 | NITROGEN CONTAINING BICYCLIC DERIVATIVES FOR TREATING PAIN AND PAIN RELATED CONDITIONS | Laboratorios del Dr. Esteve, S.A. (ES) | 2018-06-27 | — | — | EP | disclosed |
| US-6153372-A | CONTAINING ORGANIC SILVER SALT, PHOTOSENSITIVE SILVER HALIDE EMULSION, BINDER AND IMAGE FORMING LAYER | FUJI PHOTO FILM CO., LTD. (JP) | 2000-11-28 | — | — | US | disclosed |
| US-6150084-A | NUCLEATING AGENT AND DIPHOSPHORUS PENTOXIDE-DERIVED COMPOUND; ANTIFOGGING AGENT, CONTRAST | FUJI PHOTO FILM CO., LTD. (JP) | 2000-11-21 | — | — | US | disclosed |
| US-6140038-A | Heat-developable image-recording material | FUJI PHOTO FILM CO., LTD (JP) | 2000-10-31 | — | — | US | disclosed |
| EP-1045284-A1 | Heat developing method for heat developable image recording material | FUJI PHOTO FILM CO., LTD. (JP) | 2000-10-18 | — | — | EP | disclosed |
| EP-1041433-A1 | Heat-developable photosensitive material and method for forming image using the same | FUJI PHOTO FILM CO., LTD. (JP) | 2000-10-04 | — | — | EP | disclosed |
| EP-1041435-A1 | Heat-developable photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 2000-10-04 | — | — | EP | disclosed |
| EP-1041434-A1 | Heat-developable photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2000-10-04 | — | — | EP | disclosed |
| US-6100022-A | COMPRISES A NONPHOTOSENSITIVE ORGANIC SILVER SALT, A PHOTOSENSITIVE SILVER HALIDE AND A POLYMERIC BINDER HAVING GLASS TRANSITION TEMPERATURE OF-30 TO 40 DEGREE C. ON A SUPPORT, AND IMAGE FORMING LAYER CONTAINING NUCLEATING AGENT | FUJI PHOTO FILM CO., LTD. (JP) | 2000-08-08 | — | — | US | disclosed |
| EP-1020760-A2 | Heat developable image recording material | FUJI PHOTO FILM CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-6060228-A | BACKING LAYER CONTAINS A METHINE DYE HAVING SPECIFIC MAXIMUM ABSORPTION WAVELENGTH | FUJI PHOTO FILM CO., LTD. (JP) | 2000-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10806733-B2 | Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation | HBB, HBG2, MB | ABL1 542/4885GABRA1 639/4885GABRB2 261/4885 |
| US-20210032229-A1 | PYRIDINE RING-SUBSTITUTED PYRIDAZINOL COMPOUNDS AND DERIVATIVES, PREPARATION METHODS, HERBICIDAL COMPOSITIONS AND APPLICATIONS THEREOF | CBR3, CBR1, H1-0 | ABL1 943/4885GABRA1 2235/4885GABRB2 1886/4885 |
| US-20240217990-A1 | THIENOPYRROLE COMPOUNDS | SSB, TPMT, LCP2 | ABL1 692/4885GABRA1 2876/4885GABRB2 2487/4885 |
| US-20220125786-A1 | SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | HBB, HBG2, MB | ABL1 542/4885GABRA1 639/4885GABRB2 261/4885 |
| US-20210130473-A1 | TGFßR1 INHIBITOR-ASGR ANTIBODY CONJUGATES AND USES THEREOF | TGFBR2, ASGR1, TGFBR1 | ABL1 1118/4885GABRA1 405/4885GABRB2 508/4885 |
| US-20200048288-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | MAP3K6, PIK3CA, MAP3K20 | ABL1 16/4885GABRA1 4233/4885GABRB2 4116/4885 |
| US-20190160060-A1 | SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | HBB, HBG2, MB | ABL1 542/4885GABRA1 639/4885GABRB2 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.