Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TIPARP | Q7Z3E1 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24675022 | 0.87 | ALDH1A1 (0.34) | KDM4EUSP2ALDH1A1ALOX15CASP1 | |
| SCHEMBL24675034 | 0.87 | ALDH1A1 (0.34) | KDM4EUSP2ALDH1A1ALOX15CASP1 | |
| SCHEMBL24675050 | 0.86 | ALDH1A1 (0.33) | KDM4EUSP2ALDH1A1ALOX15CASP1 | |
| SCHEMBL24675033 | 0.86 | KDM4E (0.30) | KDM4EUSP2ALDH1A1ALOX15CASP1 | |
| SCHEMBL24675031 | 0.84 | PIK3CA (0.35) | KDM4EUSP2ALDH1A1ALOX15CASP1 | |
| SCHEMBL24675038 | 0.83 | VRK1 (0.36) | KDM4EUSP2ALDH1A1ALOX15CASP1 | |
| SCHEMBL24675040 | 0.81 | TIPARP (0.40) | KDM4EUSP2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL24675026 | 0.81 | TIPARP (0.33) | KDM4EUSP2ALDH1A1ALOX15CASP1 | |
| SCHEMBL29274236 | 0.76 | TIPARP (0.42) | ALDH1A1KMT2ASMN1; SMN2TIPARP | |
| SCHEMBL24675029 | 0.75 | KMT2A (0.32) | KDM4EUSP2ALDH1A1ALOX15CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022223022-A1 | FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2022-10-27 | — | — | WO | disclosed |