SCHEMBL2467516

SCHEMBL2467516

OCCc1ccc(C(F)(F)Cl)nc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TKT P29401 1/20 0.43
DAO P14920 3/20 0.38
CA2 P00918 3/20 0.38
CA1 P00915 2/20 0.38
CA12 O43570 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
TSHR P16473 1/20 0.34
HTR2A P28223 1/20 0.34
KCNH2 Q12809 1/20 0.34
KDM1A O60341 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
KDM4E B2RXH2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1259004 0.85 TKT (0.55) TKTDAOCA2CA1CA12
SCHEMBL2470939 0.84 DAO (0.39) TKTDAOHTR2AKCNH2KDM1A
SCHEMBL7996113 0.79 TRPV4 (0.36) TKTDAOCA2CA1HTR2A
SCHEMBL2466683 0.78 DAO (0.36) TKTDAOTSHRHTR2AKCNH2
SCHEMBL27855769 0.78 KDM1A (0.35) TKTDAOKCNH2KDM1AMAOA
SCHEMBL15799967 0.78 TKT (0.42) TKTDAOCA2CA1CA12
SCHEMBL2464769 0.75 DAO (0.35) DAOHTR2AKCNH2KDM1AMAOA
SCHEMBL31067892 0.75 TKT (0.49) TKTDAOCA2TSHRKDM1A
SCHEMBL14028936 0.75 TKT (0.49) TKTDAOCA2TSHRKDM1A
SCHEMBL7993760 0.74 TKT (0.48) TKTDAOCA2TSHRKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2844068-A1 SYNERGISTIC PESTICIDAL COMPOSITIONS Dow AgroSciences LLC (US) 2015-03-11 EP disclosed
WO-2013165793-A1 SYNERGISTIC PESTICIDAL COMPOSITIONS DOW AGROSCIENCES, LLC (US) 2013-11-07 WO disclosed
EP-2369921-A1 STABLE SULFOXIMINE-INSECTICIDE COMPOSITIONS Dow AgroSciences LLC (US) 2011-10-05 EP disclosed
EP-2369935-A1 STABLE INSECTICIDE COMPOSITIONS AND METHODS FOR PRODUCING SAME Dow AgroSciences LLC (US) 2011-10-05 EP disclosed
WO-2010074751-A1 STABLE SULFOXIMINE-INSECTICIDE COMPOSITIONS DOW AGROSCIENCES, LLC (US) 2010-07-01 WO disclosed
WO-2010074747-A1 STABLE INSECTICIDE COMPOSITIONS AND METHODS FOR PRODUCING SAME DOW AGROSCIENCES, LLC (US) 2010-07-01 WO disclosed
EP-2166851-A2 INCREASING PLANT VIGOR Dow AgroSciences LLC (US) 2010-03-31 EP disclosed
EP-2057121-A2 INSECTICIDAL N-SUBSTITUTED (HETEROARYL)ALKYL SULFILIMINES Dow AgroSciences LLC (US) 2009-05-13 EP disclosed
WO-2009014891-A2 INCREASING PLANT VIGOR DOW AGROSCIENCES LLC (US) 2009-01-29 WO disclosed
EP-1989184-A2 INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)ALKYL SULFOXIMINES Dow AgroSciences LLC (US) 2008-11-12 EP disclosed
WO-2008030266-A2 INSECTICIDAL N-SUBSTITUTED (HETEROARYL)ALKYL SULFILMINES DOW AGROSCIENCES LLC (US) 2008-03-13 WO disclosed
WO-2007095229-A2 INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)ALKYL SULFOXIMINES DOW AGROSCIENCES LLC (US) 2007-08-23 WO disclosed