Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TKT | P29401 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 3/20 | 0.48 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.40 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.40 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028936 | 1.00 | TKT (0.49) | TKTDAOTRPV4CA2PLAAT3 | |
| SCHEMBL7993760 | 0.95 | TKT (0.48) | TKTDAOTRPV4CA2PLAAT3 | |
| SCHEMBL1259004 | 0.89 | TKT (0.55) | TKTDAOTRPV4CA2PLAAT3 | |
| SCHEMBL991269 | 0.82 | DAO (0.48) | TKTDAOTRPV4PLAAT3PLAAT5 | |
| SCHEMBL5657097 | 0.82 | DAO (0.48) | TKTDAOTRPV4PLAAT3PLAAT5 | |
| SCHEMBL20249204 | 0.82 | CA2 (0.43) | TKTCA2LTA4HEPHX2CYP3A4 | |
| SCHEMBL12224352 | 0.82 | NFKB1 (0.50) | TKTDAOTRPV4CA2KDM1A | |
| SCHEMBL29525326 | 0.81 | TRPV4 (0.52) | TKTDAOTRPV4KDM1AMAOA | |
| SCHEMBL132198 | 0.81 | TRPV4 (0.52) | TKTDAOTRPV4KDM1AMAOA | |
| SCHEMBL18737245 | 0.81 | RAB9A (0.48) | TKTDAOTRPV4CA2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118510783-A | Spiro modulators of cholesterol biosynthesis and their use for promoting remyelination | 基因泰克公司 | 2024-08-16 | — | — | CN | disclosed |