Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24675766 | 1.00 | CNR1 (0.47) | CNR1CNR2KDM4EALDH1A1GAA | |
| SCHEMBL24675794 | 1.00 | CNR1 (0.47) | CNR1CNR2KDM4EALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL25249852 | 0.99 | CNR1 (0.47) | CNR1CNR2KDM4EALDH1A1GAA | |
| SCHEMBL24674879 | 0.95 | CNR1 (0.45) | CNR1CNR2KDM4EALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL25256065 | 0.94 | CNR1 (0.44) | CNR1CNR2KDM4EALDH1A1GAA | |
| SCHEMBL4832834 | 0.94 | LOXL2 (0.49) | CNR1CNR2KDM4EALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL4935323 | 0.92 | LOXL2 (0.48) | CNR1CNR2KDM4EALDH1A1GAA | |
| SCHEMBL4843336 | 0.90 | LOXL2 (0.50) | KDM4EALDH1A1GAALOXL2PDE3B | |
| Hydrochloric Acid SCHEMBL25298334 | 0.90 | CNR1 (0.50) | CNR1CNR2KDM4EALDH1A1GAA | |
| SCHEMBL24675114 | 0.88 | PLA2G4B (0.44) | CNR1CNR2KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129564-A1 | DEGRADERS OF GRK2 AND USES THEREOF | CYGNAL THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |