Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 14/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24675683 | 1.00 | ACACB (0.48) | ACACBCTSKABCB1ACACAHPGD | |
| SCHEMBL24675658 | 0.86 | ACACB (0.49) | ACACBCTSKACACAHPGD | |
| SCHEMBL24675892 | 0.86 | ACACB (0.49) | ACACBCTSKACACAHPGD | |
| SCHEMBL24675673 | 0.85 | CTSK (0.43) | CTSKACACALMNA | |
| SCHEMBL31737995 | 0.85 | CTSK (0.47) | CTSKGPR88 | |
| SCHEMBL24675529 | 0.83 | ACACB (0.53) | ACACBCTSKACACAHPGD | |
| SCHEMBL27225866 | 0.83 | ALDH1A1 (0.54) | ACACBCTSK | |
| SCHEMBL24675528 | 0.83 | ACACB (0.53) | ACACBCTSKACACAHPGD | |
| SCHEMBL13920480 | 0.82 | ACACB (0.51) | ACACBCTSKABCB1ACACAHPGD | |
| SCHEMBL29023015 | 0.82 | ACACB (0.49) | ACACBCTSKACACAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022159688-A9 | DEGRADERS OF GRK2 AND USES THEREOF | SONATA THERAPEUTICS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| WO-2022159688-A1 | DEGRADERS OF GRK2 AND USES THEREOF | CYGNAL THERAPEUTICS, INC. (US) | 2022-07-28 | — | — | WO | disclosed |