SCHEMBL24676033

SCHEMBL24676033

c1ccc(-c2ccc3c4ccc(-c5ccccc5)cc4n(-c4ccc(-c5ccc(-n6c7ccccc7c7ccc8sc9ccccc9c8c76)cc5)cc4)c3c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HDAC4 P56524 1/20 0.35
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
HSD17B10 Q99714 1/20 0.31
MAOB P27338 1/20 0.31
NR3C1 P04150 1/20 0.31
LIMK1 P53667 1/20 0.30
KMT2A Q03164 1/20 0.30
F9 P00740 1/20 0.30
IL1R1 P14778 1/20 0.30
PSEN1 P49768 1/20 0.30
PSEN2 P49810 1/20 0.30
APH1B Q8WW43 1/20 0.30
NCSTN Q92542 1/20 0.30
APH1A Q96BI3 1/20 0.30
PSENEN Q9NZ42 1/20 0.30
GPR3 P46089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24676351 1.00 KDM4E (0.40) KDM4EATML3MBTL1HDAC4RXRA
SCHEMBL24676625 1.00 KDM4E (0.40) KDM4EATML3MBTL1HDAC4RXRA
SCHEMBL24676614 0.94 KDM4E (0.39) KDM4EATML3MBTL1HDAC4HSD17B10
SCHEMBL19652786 0.94 KDM4E (0.39) KDM4EATML3MBTL1HDAC4HSD17B10
SCHEMBL24676407 0.94 KDM4E (0.39) KDM4EATML3MBTL1HDAC4HSD17B10
SCHEMBL24676185 0.94 KDM4E (0.39) KDM4EATML3MBTL1HDAC4HSD17B10
SCHEMBL24676218 0.94 KDM4E (0.39) KDM4EATML3MBTL1HDAC4HSD17B10
SCHEMBL24676210 0.94 KDM4E (0.39) KDM4EATML3MBTL1HDAC4HSD17B10
SCHEMBL10014543 0.94 L3MBTL1 (0.41) KDM4EATML3MBTL1HDAC4HSD17B10
SCHEMBL19653549 0.93 L3MBTL1 (0.41) KDM4EATML3MBTL1HDAC4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230033529-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-02 US disclosed
US-20220238815-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND, AND ELECTRONIC APPLIANCE IDEMITSU KOSAN CO.,LTD. (JP) 2022-07-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230033529-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE LEF1, L1CAM, RAP1A KDM4E 3096/4885ATM 2806/4885L3MBTL1 173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.