Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24676590 | 0.89 | NOTUM (0.36) | ALDH1A1KDM4ESMN1; SMN2CHRM4CYP2D6 | |
| SCHEMBL24676880 | 0.77 | PTGER4 (0.51) | — | |
| SCHEMBL24677077 | 0.75 | PTGER4 (0.52) | PDE2A | |
| SCHEMBL24676582 | 0.74 | PTGER4 (0.43) | PDE2A | |
| SCHEMBL1845684 | 0.71 | KDM4E (0.44) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL26784942 | 0.66 | BACE1 (0.39) | SMN1; SMN2 | |
| SCHEMBL25366601 | 0.65 | BACE1 (0.38) | ALDH1A1SMN1; SMN2HDAC6HPGD | |
| SCHEMBL26799801 | 0.64 | CNR2 (0.44) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL26788302 | 0.64 | CNR2 (0.44) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL26045023 | 0.64 | CNR2 (0.44) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161422-A1 | HETEROCYCLIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 深圳晶泰科技有限公司 | 2022-08-04 | — | — | WO | disclosed |