Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24676580 | 0.89 | ALDH1A1 (0.33) | NOTUMHDAC6SMN1; SMN2KDM4ECYP2D6 | |
| SCHEMBL26908087 | 0.87 | HSP90B1 (0.34) | HDAC6SMN1; SMN2TP53ALDH1A1MAPT | |
| SCHEMBL24676880 | 0.82 | PTGER4 (0.51) | PTGER4PTGDR | |
| SCHEMBL24677077 | 0.80 | PTGER4 (0.52) | PTGER4PTGDR | |
| SCHEMBL29260289 | 0.80 | PTGER4 (0.43) | PTGER4PTGDRSMN1; SMN2KDM4EPOLB | |
| SCHEMBL24676582 | 0.75 | PTGER4 (0.43) | PTGER4PTGDRHTTMAPTMEN1 | |
| SCHEMBL30516662 | 0.75 | BACE1 (0.39) | PTGER4SMN1; SMN2TP53 | |
| SCHEMBL26784942 | 0.75 | BACE1 (0.39) | PTGER4SMN1; SMN2TP53 | |
| SCHEMBL1845684 | 0.72 | KDM4E (0.44) | PTGER4PTGDRSMN1; SMN2KDM4EHTT | |
| SCHEMBL31613309 | 0.71 | PTGER4 (0.43) | PTGER4PTGDRSMN1; SMN2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399339-A1 | HETEROCYCLIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | SHENZHEN ZHONGGE BIOLOGICAL TECHNOLOGY CO., LTD. (CN) | 2023-12-14 | — | — | US | disclosed |
| EP-4286390-A1 | HETEROCYCLIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Shenzhen Zhongge Biological Technology Co., Ltd. (CN) | 2023-12-06 | — | — | EP | disclosed |
| CN-116783201-A | Heterocyclic amide derivative, preparation method and application thereof | 深圳众格生物科技有限公司 | 2023-09-19 | — | — | CN | disclosed |
| WO-2022161422-A1 | HETEROCYCLIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 深圳晶泰科技有限公司 | 2022-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399339-A1 | HETEROCYCLIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | PTGER4, PTGER1, EPB41 | NOTUM 4/4885HDAC6 1432/4885PTGER4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.