SCHEMBL24676880

SCHEMBL24676880

Cc1sc2ccn(Cc3ccc(S(F)(F)(F)(F)F)cc3)c2c1C(=O)NC(C)c1ccc(C(=O)O)cc1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 20/20 0.51
PTGDR Q13258 8/20 0.51
PTGER2 P43116 6/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28486614 0.89 PTGER4 (0.64) PTGER4PTGDRPTGER2
SCHEMBL1956242 0.89 PTGER4 (0.64) PTGER4PTGDRPTGER2
SCHEMBL1954049 0.89 PTGER4 (0.66) PTGER4PTGDRPTGER2
SCHEMBL1847632 0.89 PTGER4 (0.66) PTGER4PTGDRPTGER2
SCHEMBL24677001 0.83 PTGER4 (0.54) PTGER4PTGDRPTGER2
SCHEMBL24676590 0.82 NOTUM (0.36) PTGER4PTGDR
SCHEMBL12550104 0.81 PTGER4 (0.44) PTGER4PTGDRPTGER2
SCHEMBL24677077 0.81 PTGER4 (0.52) PTGER4PTGDRPTGER2
SCHEMBL29260289 0.77 PTGER4 (0.43) PTGER4PTGDRPTGER2
SCHEMBL24676580 0.77 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399339-A1 HETEROCYCLIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF SHENZHEN ZHONGGE BIOLOGICAL TECHNOLOGY CO., LTD. (CN) 2023-12-14 US disclosed
US-20230399339-A1 HETEROCYCLIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF SHENZHEN ZHONGGE BIOLOGICAL TECHNOLOGY CO., LTD. (CN) 2023-12-14 US disclosed
WO-2022161422-A1 HETEROCYCLIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 深圳晶泰科技有限公司 2022-08-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399339-A1 HETEROCYCLIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF PTGER4, PTGER1, EPB41 PTGER4 1/4885PTGDR 78/4885PTGER2 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.