Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CHKA | P35790 | 11/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4339091 | 0.98 | ALDH1A1 (0.61) | ALDH1A1KDM4ERAB9ALMNACHKA | |
| Hydrochloric Acid SCHEMBL2460504 | 0.89 | ALDH1A1 (0.79) | ALDH1A1KDM4ERAB9ALMNACHKA | |
| Hydrochloric Acid SCHEMBL2463096 | 0.89 | ALDH1A1 (0.55) | ALDH1A1KDM4ERAB9ALMNACHKA | |
| Benzyl Viologen SCHEMBL1930045 | 0.88 | ALDH1A1 (0.78) | ALDH1A1KDM4ERAB9ALMNACHKA | |
| Benzyl Viologen SCHEMBL599497 | 0.86 | ALDH1A1 (0.75) | ALDH1A1KDM4ERAB9ALMNACHKA | |
| Hydrochloric Acid SCHEMBL1248547 | 0.86 | ALDH1A1 (0.75) | ALDH1A1KDM4ERAB9ALMNACHKA | |
| Benzyl Viologen SCHEMBL1108041 | 0.86 | ALDH1A1 (0.74) | ALDH1A1KDM4ERAB9ALMNACHKA | |
| Hydrochloric Acid SCHEMBL2466857 | 0.86 | ALDH1A1 (0.53) | ALDH1A1KDM4ERAB9ALMNACHKA | |
| Hydrochloric Acid SCHEMBL2464589 | 0.85 | ALDH1A1 (0.51) | ALDH1A1KDM4ERAB9ALMNACHKA | |
| Benzyl Viologen SCHEMBL4089383 | 0.84 | ALDH1A1 (0.71) | ALDH1A1KDM4ERAB9ALMNACHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8014056-B2 | Display element and method of driving the same | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20100091353-A1 | DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME | KONICA MINOLTA HOLDINGS, INC. (JP) | 2010-04-15 | — | — | US | disclosed |