Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 6/20 | 0.53 |
| ▸ | F13A1 | P00488 | 4/20 | 0.53 |
| ▸ | TGM1 | P22735 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TGM6 | O95932 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29727262 | 0.87 | TGM2 (0.56) | PKMSMN1; SMN2HTTTGM2F13A1 | |
| SCHEMBL19868239 | 0.85 | TGM2 (0.58) | PKMSMN1; SMN2HTTTGM2F13A1 | |
| SCHEMBL5121359 | 0.82 | ALDH1A1 (0.61) | PKMSMN1; SMN2HTTTGM2F13A1 | |
| SCHEMBL26341552 | 0.81 | ALDH1A1 (0.62) | PKMSMN1; SMN2HTTTGM2F13A1 | |
| SCHEMBL17592966 | 0.81 | TSHR (0.63) | PKMSMN1; SMN2HTTTGM2F13A1 | |
| SCHEMBL24676790 | 0.80 | ALDH1A1 (0.53) | PKMSMN1; SMN2HTTTGM2F13A1 | |
| SCHEMBL22191441 | 0.80 | ALDH1A1 (0.64) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL24676807 | 0.79 | TSHR (0.58) | PKMSMN1; SMN2HTTTGM2F13A1 | |
| SCHEMBL17593000 | 0.78 | TGM2 (0.54) | PKMSMN1; SMN2HTTTGM2F13A1 | |
| SCHEMBL13402357 | 0.77 | ALDH1A1 (0.67) | PKMSMN1; SMN2HTTTGM2F13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |