Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 8/20 | 0.33 |
| ▸ | CDK7 | P50613 | 6/20 | 0.33 |
| ▸ | CCNK | O75909 | 4/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 9/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.32 |
| ▸ | CDK4 | P11802 | 6/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 6/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.32 |
| ▸ | CCND1 | P24385 | 5/20 | 0.32 |
| ▸ | CCND3 | P30281 | 5/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.31 |
| ▸ | CCNH | P51946 | 5/20 | 0.31 |
| ▸ | CDK1 | P06493 | 2/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.31 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29754894 | 1.00 | CDK9 (0.33) | CDK9CDK7CCNKCDK12CSNK1A1 | |
| SCHEMBL24676597 | 0.89 | CDK2 (0.37) | CDK9CDK7CCNKCDK12CSNK1A1 | |
| SCHEMBL29754815 | 0.89 | CDK2 (0.37) | CDK9CDK7CCNKCDK12CSNK1A1 | |
| SCHEMBL24677041 | 0.82 | CDK6 (0.34) | CDK9CDK7CCNKCDK12CSNK1A1 | |
| SCHEMBL29755036 | 0.81 | CDK2 (0.41) | CDK2CDK4CDK6CCNA2CCND1 | |
| SCHEMBL29754857 | 0.81 | CDK2 (0.41) | CDK2CDK4CDK6CCNA2CCND1 | |
| SCHEMBL24677030 | 0.81 | CDK2 (0.41) | CDK2CDK4CDK6CCNA2CCND1 | |
| SCHEMBL24675994 | 0.81 | CDK2 (0.41) | CDK2CDK4CDK6CCNA2CCND1 | |
| SCHEMBL24676684 | 0.80 | CDK2 (0.43) | CDK9CDK7CDK2CCNT1CDK4 | |
| SCHEMBL24676764 | 0.79 | CDK2 (0.36) | CDK9CDK7CCNKCDK12CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |