SCHEMBL24677324

SCHEMBL24677324

Cc1ccc2c(-c3ccc4sc5ccccc5c4c3)ncnc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.41
MAP4K4 O95819 1/20 0.36
GPR3 P46089 1/20 0.36
CYP1A2 P05177 1/20 0.36
PTPN7 P35236 1/20 0.35
PTPN12 Q05209 1/20 0.35
PTPN22 Q9Y2R2 1/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35
GABRB2 P47870 1/20 0.35
GABRA4 P48169 1/20 0.35
GABRE P78334 1/20 0.35
GABRA6 Q16445 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20146314 0.86 ADORA2A (0.56) ADORA2AMAP4K4GPR3CYP1A2ALDH1A1
SCHEMBL19781959 0.81 ADORA2A (0.56) ADORA2AMAP4K4GPR3ALDH1A1MAPT
SCHEMBL13584672 0.77 ADORA2A (0.62) ADORA2AMAP4K4ALDH1A1MAPTSMN1; SMN2
SCHEMBL25162372 0.74 MAPT (0.42) ADORA2AGPR3GABRPGABRDGABRA1
SCHEMBL9917121 0.74 GPR3 (0.52) GPR3CYP1A2PTPN7PTPN12PTPN22
SCHEMBL9917184 0.74 GPR3 (0.52) GPR3CYP1A2PTPN7PTPN12PTPN22
SCHEMBL9917143 0.74 GPR3 (0.52) GPR3CYP1A2PTPN7PTPN12PTPN22
SCHEMBL257003 0.73 GPR3 (0.61) GPR3CYP1A2PTPN7PTPN12PTPN22
SCHEMBL18667997 0.73 ADORA2A (0.42) ADORA2AGPR3CYP1A2PTPN7PTPN12
SCHEMBL24796188 0.73 ADORA2A (0.42) ADORA2AMAP4K4ALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220281898-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220281898-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OXSR1, C1R ADORA2A 1658/4885MAP4K4 4493/4885GPR3 349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.