SCHEMBL19781959

SCHEMBL19781959

c1ccc2c(-c3ccc4c(c3)sc3ccccc34)ncnc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.56
ALDH1A1 P00352 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CAMKK1 Q8N5S9 1/20 0.43
CAMKK2 Q96RR4 1/20 0.43
GRM4 Q14833 1/20 0.43
GPR3 P46089 1/20 0.42
PIK3CD O00329 2/20 0.41
PIK3CA P42336 2/20 0.41
PIK3CB P42338 2/20 0.41
MTOR P42345 2/20 0.41
PIK3CG P48736 2/20 0.41
AAK1 Q2M2I8 1/20 0.40
LIMK1 P53667 6/20 0.39
PI4KA P42356 1/20 0.39
PI4K2B Q8TCG2 1/20 0.39
PI4K2A Q9BTU6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20146314 0.91 ADORA2A (0.56) ADORA2AALDH1A1MAPTHPGDRAB9A
SCHEMBL24677324 0.81 ADORA2A (0.41) ADORA2AALDH1A1MAPTHPGDRAB9A
SCHEMBL15040965 0.81 ALDH1A1 (0.49) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL23259465 0.80 ADORA2A (0.67) ADORA2AALDH1A1CAMKK1CAMKK2GRM4
SCHEMBL25462023 0.79 ADORA2A (0.45) ADORA2AALDH1A1MAPTHPGDRAB9A
SCHEMBL21890675 0.79 MAPT (0.50) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL19781960 0.77 ALDH1A1 (0.41) ADORA2AALDH1A1MAPTHPGDRAB9A
SCHEMBL18942945 0.77 ALDH1A1 (0.56) ADORA2AALDH1A1MAPTHPGDRAB9A
SCHEMBL19989725 0.77 ALDH1A1 (0.41) ADORA2AALDH1A1MAPTHPGDRAB9A
SCHEMBL19986164 0.77 ADORA2A (0.42) ADORA2AALDH1A1MAPTHPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4282863-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-11-29 EP disclosed
US-20220216433-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-07-07 US disclosed
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220216433-A1 ELECTROLUMINESCENT DEVICE EML4, EMC2, L1CAM ADORA2A 2665/4885ALDH1A1 99/4885MAPT 1603/4885
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OR51E2, OXER1 ADORA2A 3814/4885ALDH1A1 158/4885MAPT 2618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.