SCHEMBL24677417

SCHEMBL24677417

C=C/C=C\C=C(/C)c1nc(-c2ccc(-c3cccc(-c4ccccc4)c3)cc2)nc(-c2ccc(-n3c4ccccc4c4cc(-n5c6ccccc6c6ccccc65)ccc43)cc2)n1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.32
RAC2 P15153 1/20 0.32
RAC3 P60763 1/20 0.32
CDC42 P60953 1/20 0.32
RAC1 P63000 1/20 0.32
AKR1C4 P17516 1/20 0.31
AKR1C3 P42330 1/20 0.31
AKR1C2 P52895 1/20 0.31
AKR1C1 Q04828 1/20 0.31
TSPO P30536 1/20 0.31
HDAC4 P56524 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
RXRA P19793 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26051491 0.91 PTGER4 (0.35) PTGER4RAC2RAC3CDC42RAC1
SCHEMBL23277705 0.90 PTGER4 (0.33) PTGER4AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL23265814 0.90 KDM4E (0.35) PTGER4AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL24663013 0.88 PTGER4 (0.36) PTGER4TSPOKDM4EATML3MBTL1
SCHEMBL20821878 0.88 PTGER4 (0.34) PTGER4KDM4EATML3MBTL1
SCHEMBL24813357 0.85 PTGER4 (0.35) PTGER4TSPOKDM4EATML3MBTL1
SCHEMBL23771478 0.84 PTGER4 (0.34) PTGER4RAC2RAC3CDC42RAC1
SCHEMBL20887797 0.84 PTGER4 (0.32) PTGER4
SCHEMBL20887796 0.84 PTGER4 (0.32) PTGER4
SCHEMBL18821134 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11485706-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11485706-B2 Organic electroluminescent materials and devices SOD1, L1CAM, EPCAM PTGER4 3211/4885RAC2 3737/4885RAC3 3698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.