Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18821134 | 0.90 | — | — | |
| SCHEMBL24677417 | 0.90 | PTGER4 (0.32) | PTGER4AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL26051491 | 0.90 | PTGER4 (0.35) | PTGER4TSPOKDM4EATML3MBTL1 | |
| SCHEMBL23265814 | 0.89 | KDM4E (0.35) | PTGER4AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL24663013 | 0.87 | PTGER4 (0.36) | PTGER4TSPOKDM4EATML3MBTL1 | |
| SCHEMBL20887797 | 0.85 | PTGER4 (0.32) | PTGER4 | |
| SCHEMBL24813357 | 0.85 | PTGER4 (0.35) | PTGER4TSPOKDM4EATML3MBTL1 | |
| SCHEMBL22916382 | 0.85 | PTGER4 (0.39) | PTGER4TSPOKDM4EATML3MBTL1 | |
| SCHEMBL18821131 | 0.84 | — | — | |
| SCHEMBL20887796 | 0.83 | PTGER4 (0.32) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10991892-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2021-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10991892-B2 | Materials for organic electroluminescent devices | MT-CO3, MT-ND3, MT-ND5 | PTGER4 1508/4885AKR1C4 4110/4885AKR1C3 4037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.