Sugi Predict

Sugi Predict / Compounds / SCHEMBL24677429

SCHEMBL24677429

SCHEMBL24677429

c1ccc(-n2c3ccccc3c3cc4c(cc32)c2ccccc2n4-c2ccc3c(c2)c2ccccc2n3-c2ccc3ccccc3c2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.56
▸ L3MBTL1 Q9Y468 2/20 0.56
▸ ATM Q13315 1/20 0.56
▸ PMM2 O15305 1/20 0.40
▸ MPI P34949 1/20 0.40
▸ PHOSPHO1 Q8TCT1 1/20 0.40
▸ F2 P00734 1/20 0.39
▸ F10 P00742 1/20 0.39
▸ PRSS1 P07477 1/20 0.39
▸ HPGD P15428 2/20 0.39
▸ PTPN1 P18031 2/20 0.37
▸ ALDH1A1 P00352 4/20 0.37
▸ TSHR P16473 1/20 0.37
▸ RAB9A P51151 2/20 0.37
▸ NPC1 O15118 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ HSP90AA1 P07900 1/20 0.37
▸ SIGMAR1 Q99720 2/20 0.36
▸ BACE1 P56817 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19769592 1.00 KDM4E (0.56) KDM4EL3MBTL1ATMPMM2MPI
SCHEMBL10027575 0.97 KDM4E (0.60) KDM4EL3MBTL1ATMPMM2MPI
SCHEMBL19342718 0.95 KDM4E (0.55) KDM4EL3MBTL1ATMPMM2MPI
SCHEMBL19769526 0.94 KDM4E (0.53) KDM4EL3MBTL1ATMPMM2MPI
SCHEMBL19653764 0.93 KDM4E (0.51) KDM4EL3MBTL1ATMPMM2MPI
SCHEMBL19653710 0.93 KDM4E (0.51) KDM4EL3MBTL1ATMPMM2MPI
SCHEMBL19653497 0.93 KDM4E (0.51) KDM4EL3MBTL1ATMPMM2MPI
SCHEMBL17689958 0.92 L3MBTL1 (0.58) KDM4EL3MBTL1ATMF2F10
SCHEMBL25098798 0.92 L3MBTL1 (0.58) KDM4EL3MBTL1ATMF2F10
SCHEMBL23233630 0.92 KDM4E (0.58) KDM4EL3MBTL1ATMPMM2MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11723269-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-08 — — US disclosed
US-20230159550-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 — — US disclosed
US-20230159550-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 — — US disclosed
US-11485706-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-11-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11485706-B2 Organic electroluminescent materials and devices SOD1, L1CAM, EPCAM KDM4E 3594/4885L3MBTL1 1135/4885ATM 1277/4885
US-20230159550-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 KDM4E 2090/4885L3MBTL1 888/4885ATM 3709/4885
US-11723269-B2 Organic electroluminescent materials and devices PUF60, CD99, DDT KDM4E 3163/4885L3MBTL1 1292/4885ATM 3362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.