Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL890089 | 0.73 | CYP1A2 (0.44) | CYP1A2TDP1HTTLMNA | |
| SCHEMBL7684250 | 0.70 | — | — | |
| SCHEMBL10049272 | 0.70 | — | — | |
| SCHEMBL14500150 | 0.70 | — | — | |
| SCHEMBL16079972 | 0.69 | — | — | |
| SCHEMBL24677736 | 0.68 | — | — | |
| SCHEMBL26919587 | 0.68 | NCF1 (0.34) | — | |
| SCHEMBL24677726 | 0.67 | — | — | |
| SCHEMBL15164297 | 0.67 | ALDH1A1 (0.49) | CYP1A2TDP1HTTLMNA | |
| SCHEMBL24677745 | 0.66 | CYP1A2 (0.31) | CYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188819-A1 | SOS1 PROTEOLYSIS MODULATOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 苏州泽璟生物制药股份有限公司 | 2022-09-15 | — | — | WO | disclosed |