Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 6/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | ADAMTS4 | O75173 | 6/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 6/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 5/20 | 0.42 |
| ▸ | MMP3 | P08254 | 5/20 | 0.42 |
| ▸ | MMP13 | P45452 | 5/20 | 0.42 |
| ▸ | MMP14 | P50281 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4816398 | 0.78 | HDAC3 (0.53) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL446351 | 0.76 | HDAC3 (0.58) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL2406715 | 0.76 | TAS1R3 (0.50) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL4928945 | 0.76 | HDAC3 (0.67) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL444823 | 0.76 | HDAC3 (0.51) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL17254439 | 0.76 | HDAC3 (0.51) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL29827697 | 0.74 | HDAC3 (0.61) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL445062 | 0.74 | HDAC1 (0.64) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL4920463 | 0.73 | HDAC2 (0.69) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL6239408 | 0.72 | HDAC3 (0.60) | HDAC3HDAC1HDAC2HDAC6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106632-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |