Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12869168 | 0.81 | LMNA (0.83) | ALDH1A1POLBLMNASMN1; SMN2KMT2A | |
| SCHEMBL486324 | 0.77 | LMNA (1.00) | ALDH1A1POLBLMNASMN1; SMN2KMT2A | |
| SCHEMBL5682463 | 0.75 | LMNA (0.73) | ALDH1A1POLBLMNAHTTSMN1; SMN2 | |
| SCHEMBL2472316 | 0.74 | NPSR1 (0.54) | ALDH1A1LMNAKMT2AMAPTKDM4E | |
| SCHEMBL12869188 | 0.74 | LMNA (0.71) | ALDH1A1POLBLMNASMN1; SMN2KMT2A | |
| SCHEMBL486694 | 0.73 | LMNA (0.74) | ALDH1A1LMNASMN1; SMN2KMT2AUSP2 | |
| SCHEMBL9433082 | 0.72 | MAPT (1.00) | ALDH1A1POLBLMNASMN1; SMN2KMT2A | |
| SCHEMBL12869186 | 0.69 | MAPT (0.63) | ALDH1A1POLBLMNAKMT2AUSP2 | |
| SCHEMBL24880296 | 0.68 | LMNA (0.61) | POLBLMNAHTTSMN1; SMN2KMT2A | |
| SCHEMBL486405 | 0.67 | LMNA (0.59) | ALDH1A1LMNASMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011121068-A1 | AMINO DERIVATIVES OF CYCLOHEX-2-ENONE, THEIR PREPARATION AND USE AS ANTIOXIDANTS | ABIOGEN PHARMA S.P.A. (IT) | 2011-10-06 | — | — | WO | disclosed |
| EP-2371816-A1 | Aminocyclohexenone, their preparation and use as medicament against oxidative stress | ABIOGEN PHARMA S.p.A. (IT) | 2011-10-05 | — | — | EP | disclosed |