Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29414003 | 0.84 | NQO2 (0.46) | NQO2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL21459066 | 0.84 | NQO2 (0.46) | NQO2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL29964335 | 0.80 | NQO2 (0.41) | NQO2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL25165622 | 0.78 | NQO2 (0.40) | NQO2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL30050649 | 0.77 | LPL (0.32) | LPLLIPG | |
| SCHEMBL27960198 | 0.76 | LPL (0.34) | LPLLIPG | |
| SCHEMBL28575128 | 0.73 | TRPM4 (0.33) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL24311869 | 0.72 | LPL (0.35) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| Ammonia Solution, Strong SCHEMBL28105416 | 0.71 | LPL (0.35) | LPLLIPG | |
| SCHEMBL28049248 | 0.71 | LPL (0.39) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188729-A1 | FUSED RING DERIVATIVES USEFUL AS KRAS G12D INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-09-15 | — | — | WO | disclosed |