SCHEMBL28049248

SCHEMBL28049248

CC1(C)COB(c2ccc3c4ccccc4c4ccccc4c3c2)OC1(C)C

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LPL P06858 7/20 0.39
LIPG Q9Y5X9 7/20 0.39
PRMT5 O14744 1/20 0.35
WDR77 Q9BQA1 1/20 0.35
ROCK1 Q13464 1/20 0.32
EGFR P00533 1/20 0.32
CSF1R P07333 1/20 0.30
P4HB P07237 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15456760 0.82 LPL (0.56) LPLLIPGPRMT5WDR77ROCK1
SCHEMBL311849 0.82 LPL (0.56) LPLLIPGPRMT5WDR77ROCK1
SCHEMBL21764502 0.82 LPL (0.56) LPLLIPGPRMT5WDR77ROCK1
SCHEMBL29787170 0.82 LPL (0.56) LPLLIPGPRMT5WDR77ROCK1
SCHEMBL17548647 0.82 LPL (0.56) LPLLIPGPRMT5WDR77ROCK1
SCHEMBL2015694 0.82 LPL (0.56) LPLLIPGPRMT5WDR77ROCK1
SCHEMBL16583519 0.82 LPL (0.46) LPLLIPGP4HB
SCHEMBL27921959 0.80 LIPG (0.50) LPLLIPGP4HB
SCHEMBL28827167 0.80 MAPT (0.39)
SCHEMBL28264212 0.80 KDM4E (0.42) LPLLIPGPRMT5WDR77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105358533-A Heterocyclic compound and organic light-emitting device using the same HEESUNG MAT LTD 2016-02-24 CN disclosed