Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.44 |
| ▸ | PARP11 | Q9NR21 | 2/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | FYN | P06241 | 3/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29914419 | 1.00 | ASIC3 (0.52) | ASIC3MAPK1PARP10PARP11PDE3B | |
| SCHEMBL24680781 | 0.92 | MAPK1 (0.48) | ASIC3MAPK1PARP10PARP11KCNH2 | |
| SCHEMBL29914564 | 0.92 | MAPK1 (0.48) | ASIC3MAPK1PARP10PARP11KCNH2 | |
| SCHEMBL29914548 | 0.91 | MAPK1 (0.44) | ASIC3MAPK1PARP10PARP11WDR5 | |
| SCHEMBL24680880 | 0.91 | MAPK1 (0.44) | ASIC3MAPK1PARP10PARP11WDR5 | |
| SCHEMBL24680849 | 0.91 | MAPK1 (0.55) | ASIC3MAPK1PARP10PARP11PDE3B | |
| SCHEMBL29914518 | 0.88 | MAPK1 (0.42) | ASIC3MAPK1PARP10PARP11WDR5 | |
| SCHEMBL24681143 | 0.88 | MAPK1 (0.42) | ASIC3MAPK1PARP10PARP11WDR5 | |
| SCHEMBL31079368 | 0.86 | ASIC3 (0.49) | ASIC3MAPK1PARP10PARP11PDE3B | |
| SCHEMBL24681081 | 0.84 | MAPK1 (0.46) | ASIC3MAPK1PARP10PARP11PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022226667-A1 | SUBSTITUTED AMINO PYRIDINE COMPOUNDS AS INHIBITORS OF THE HAEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2022-11-03 | — | — | WO | disclosed |