Hydrochloric Acid

Hydrochloric Acid

SCHEMBL2468196

CCCCCC[S+](CC)CCCCCC.[Cl-]

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
THRB P10828 1/20 0.47
DNM1 Q05193 6/20 0.38
ALDH1A1 P00352 3/20 0.36
LMNA P02545 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HSD17B10 Q99714 1/20 0.36
SLC22A1 O15245 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29576283 0.95 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
Hydrochloric Acid SCHEMBL29576528 0.95 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
Hydrochloric Acid SCHEMBL29576262 0.94 TSHR (0.47) TSHRTHRBDNM1ALDH1A1LMNA
Hydrochloric Acid SCHEMBL29576487 0.94 TSHR (0.47) TSHRTHRBDNM1ALDH1A1LMNA
Hydrochloric Acid SCHEMBL9344378 0.94 TSHR (0.47) TSHRTHRBDNM1ALDH1A1LMNA
Hydrochloric Acid SCHEMBL29441392 0.94 TSHR (0.47) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL29441390 0.92 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL29441415 0.92 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL4233902 0.91 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL4239091 0.91 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231566-B1 PROCESS FOR THE PURIFICATION OF CHLORINATED BUTADIENES DU PONT (US) 2017-03-29 EP disclosed
EP-2231567-B1 PROCESS FOR PRODUCTION OF 2,3-DICHLOROBUTADIENE-1,3 DU PONT (US) 2013-10-23 EP disclosed
US-20110313216-A1 PROCESS FOR PRODUCTION OF 2,3-DICHLOROBUTADIENE-1,3 DUPONT PERFORMANCE ELASTOMERS LLC 2011-12-22 US disclosed
US-8030531-B2 Process for production of 2,3-dichlorobutadiene-1,3 DUPONT PERFORMANCE ELASTOMERS LLC (US) 2011-10-04 US disclosed
US-8026400-B2 Process for production of 2,3-dichlorobutadiene-1,3 DUPONT PERFORMANCE ELASTOMERS LLC (US) 2011-09-27 US disclosed
EP-2231567-A2 PROCESS FOR PRODUCTION OF 2,3-DICHLOROBUTADIENE-1,3 DuPont Performance Elastomers L.L.C. (US) 2010-09-29 EP disclosed
EP-2231566-A2 PROCESS FOR PURIFICATION OF CHLORINATED ALKENES DuPont Performance Elastomers L.L.C. (US) 2010-09-29 EP disclosed
WO-2009085837-A2 PROCESS FOR PRODUCTION OF 2,3-DICHLOROBUTADIENE-1,3 DUPONT PERFORMANCE ELASTOMERS L.L.C. (US) 2009-07-09 WO disclosed
WO-2009085846-A2 PROCESS FOR PURIFICATION OF CHLORINATED ALKENES DUPONT PERFORMANCE ELASTOMERS L.L.C. (US) 2009-07-09 WO disclosed
US-20090163746-A1 Process for production of 2,3-dichlorobutadiene-1,3 DENKA PERFORMANCE ELASTOMER LLC 2009-06-25 US disclosed
US-20090163745-A1 PROCESS FOR PRODUCTION OF 2,3-DICHLOROBUTADIENE-1,3 DENKA PERFORMANCE ELASTOMER LLC 2009-06-25 US disclosed
EP-0429967-B1 Process for the liquid phase chlorination of 1,3-butadiene DU PONT (US) 1994-10-05 EP disclosed
US-5077443-A In evaporatively coded reactor with solvent, catalyst and free radical inhibitor E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-12-31 US disclosed
EP-0429967-A1 Process for the liquid phase chlorination of 1,3-butadiene E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-06-05 EP disclosed