Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29441392 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL29576487 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL29576262 | 1.00 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL4230550 | 0.97 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL9318550 | 0.97 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL4233902 | 0.97 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL4239091 | 0.97 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL4235319 | 0.97 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL29441396 | 0.97 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL2468196 | 0.94 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499743-B1 | Two step process for sweetening a sour hydrocarbon fraction | UOP INC (US) | 1994-07-20 | — | — | EP | disclosed |
| US-5273646-A | Adding aqueous ammonium hydroxide, metal chelate and an onium compound to the hydrocarbon fraction containing an oxidizer and base | UOP (US) | 1993-12-28 | — | — | US | disclosed |
| US-5204306-A | Oxidizing mercaptans to disulfides with metal chelate catalyst and an onium component | UOP (US) | 1993-04-20 | — | — | US | disclosed |
| EP-0396934-B1 | CAUSTIC-FREE SWEETENING OF SOUR HYDROCARBON STREAMS | UOP (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5180484-A | Oxidation in presence of ammonium hydroxide, metal chelate and onium compound | UOP (US) | 1993-01-19 | — | — | US | disclosed |
| EP-0499743-A1 | Two step process for sweetening a sour hydrocarbon fraction | UOP (US) | 1992-08-26 | — | — | EP | disclosed |
| US-5093296-A | Caustic free liquid/liquid process for sweetening a sour hydrocarbon fraction | UOP (US) | 1992-03-03 | — | — | US | disclosed |
| US-5064525-A | Catalysis; hydrogenation | UOP (US) | 1991-11-12 | — | — | US | disclosed |
| EP-0396934-A1 | Caustic-free sweetening of sour hydrocarbon streams | UOP (US) | 1990-11-14 | — | — | EP | disclosed |
| EP-0394571-A1 | Use of a novel catalytic composite for sweetening of sour petroleum distillate | UOP (US) | 1990-10-31 | — | — | EP | disclosed |
| US-4908122-A | Contacting hydrocarbon in the presence of an oxidizing agent with a catalytic composite to oxidize mercaptans to disulfides | UOP (US) | 1990-03-13 | — | — | US | disclosed |
| US-4897180-A | Catalytic composite and process for mercaptan sweetening | UOP (US) | 1990-01-30 | — | — | US | disclosed |
| US-4824818-A | OXIDATION CATALYST CONTAINING METAL CHELATE AND ONIUM COMPOUND | UOP INC. (US) | 1989-04-25 | — | — | US | disclosed |