Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30701645 | 1.00 | MAPT (0.39) | MAPTLMNAALOX12ALOX15KMT2A | |
| SCHEMBL24682166 | 0.94 | ALOX5 (0.41) | MAPTLMNAALOX12ALOX15KMT2A | |
| SCHEMBL30701702 | 0.94 | ALOX5 (0.41) | MAPTLMNAALOX12ALOX15KMT2A | |
| SCHEMBL29799918 | 0.92 | KMT2A (0.45) | MAPTLMNAALOX12ALOX15KMT2A | |
| SCHEMBL24683204 | 0.92 | KMT2A (0.45) | MAPTLMNAALOX12ALOX15KMT2A | |
| SCHEMBL24683860 | 0.91 | HSP90AA1 (0.36) | MAPTLMNAKMT2ATSHRGAA | |
| SCHEMBL29799884 | 0.91 | HSP90AA1 (0.36) | MAPTLMNAKMT2ATSHRGAA | |
| SCHEMBL24683856 | 0.84 | ALOX5 (0.43) | MAPTLMNAALOX12ALOX15KMT2A | |
| SCHEMBL30701677 | 0.84 | ALOX5 (0.43) | MAPTLMNAALOX12ALOX15KMT2A | |
| SCHEMBL24682815 | 0.82 | HSP90AA1 (0.39) | MAPTLMNAKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222630-A | 2-acetamido-6-hydroxy-benzothiophene derivatives having antiviral activity | OTC制药公司(JSC) | 2023-12-12 | — | — | CN | disclosed |
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |